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Ohio State vs. Indiana Prediction, Odds, Picks for 2025 Huge Ten Championship
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Ohio State vs. Indiana Prediction, Odds, Picks for 2025 Huge Ten Championship

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Last updated: December 6, 2025 1:26 pm
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Published: December 6, 2025
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Contents
Ohio State vs. Indiana Game Information & OddsOhio State vs. Indiana PredictionOhio State vs. Indiana Betting InsightsOhio State vs. Indiana: Head-to-HeadOhio State vs. Indiana: 2025 Stats ComparabilityOhio State 2025 Key GamersIndiana 2025 Key Gamers

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In this season’s Big Ten Championship Game the Ohio State Buckeyes are the favorites, but by less than a touchdown (-4) over the Indiana Hoosiers. Lucas Oil Stadium will host the matchup on December 6, 2025, starting at 8 p.m. ET on FOX. An over/under of 47.5 is set for the contest.

The Buckeyes’ last contest was against the Michigan Wolverines, and they won by a score of 27-9. Last time out, the Hoosiers defeated the Purdue Boilermakers, with 56-3 being the final score.

Keep up with college football all season on FOX Sports.

Ohio State vs. Indiana Game Information & Odds

  • When: Saturday, December 6, 2025 at 8 p.m. ET
  • Location: Lucas Oil Stadium in Indianapolis, Indiana
  • TV: FOX
  • Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Ohio State vs. Indiana Prediction

Take Ohio State over Indiana at the moment within the Huge Ten Championship sport. The Buckeyes, with their expertise and depth, have a powerful likelihood to manage this matchup. Ohio State has dominated all season by scoring 37 factors per sport and permitting solely 7.8.

Indiana has been spectacular with an offense placing up 44.3 factors per sport, however Ohio State’s protection matches up nicely towards the Hoosiers’ run-heavy method. The Buckeyes’ entrance seven is bodily sufficient to clog dashing lanes, and their secondary stays tight in protection, which limits explosive performs.

Julian Sayin has delivered all 12 months with 3,065 passing yards and 30 touchdowns. Bo Jackson continues to anchor the bottom sport with 952 dashing yards.

I anticipate Ohio State to win by 7 with a projected ultimate rating of 24-17. The Over/Underneath is 47.5, and a lower-scoring sport feels seemingly with each defenses able to controlling lengthy stretches.

  • Pick ATS: Ohio State (-4)
  • Pick OU: Under (47.5)
  • Prediction: Ohio State 24, Indiana 17

Ohio State vs. Indiana Betting Insights

  • Based on the spread and over/under, the implied score for the tilt is Buckeyes 26, Hoosiers 22.
  • The Buckeyes have a 65.8% chance to win this meeting per the moneyline’s implied probability. The Hoosiers hold a 38.5% implied probability.
  • Ohio State has compiled a 10-2-0 record against the spread this season.
  • Indiana has compiled a 7-5-0 record against the spread this year.

Ohio State vs. Indiana: Head-to-Head

  • In their past four head-to-head meetings, Ohio State has defeated Indiana four times.
  • The last four times the Buckeyes have gone up against the Hoosiers, they have posted a 3-1 record against the spread. The scoring has gone over the total on three occasions.
  • In their last four head-to-head matchups, Ohio State has tallied 171 points versus Indiana, while surrendering only 39 points.

Ohio State vs. Indiana: 2025 Stats Comparability

 Ohio StateIndiana
Off. Factors per Recreation (Rank)37 (13)44.3 (2)
Def. Factors per Recreation (Rank)7.8 (1)10.9 (2)
Turnovers Allowed (Rank)8 (4)7 (3)
Turnovers Pressured (Rank)12 (101)24 (7)

Ohio State 2025 Key Gamers

IdentifyPlaceStats
Julian SayinQB3,065 YDS (78.9%) / 30 TD / 5 INT
Jeremiah SmithWR72 REC / 942 YDS / 11 TD / 85.6 YPG
Bo JacksonRB952 YDS / 5 TD / 86.5 YPG / 6.3 YPC
17 REC / 187 REC YDS / 1 REC TD / 23.4 REC YPG
Carnell TateWR44 REC / 793 YDS / 8 TD / 79.3 YPG
Caden CurryDL47 TKL / 12 TFL / 9 SACK
Arvell ReeseLB61 TKL / 8 TFL / 6.5 SACK
Sonny KindsLB64 TKL / 4 TFL / 0.5 SACK / 1 INT
Kayden McDonaldDL45 TKL / 6 TFL / 3 SACK

Indiana 2025 Key Gamers

IdentifyPlaceStats
Fernando MendozaQB2,758 YDS (72%) / 32 TD / 5 INT
243 RUSH YDS / 6 RUSH TD / 20.3 RUSH YPG
Omar Cooper Jr.WR59 REC / 828 YDS / 11 TD / 69 YPG
Roman HembyRB866 YDS / 6 TD / 72.2 YPG / 5.3 YPC
13 REC / 153 REC YDS / 0 REC TD / 15.3 REC YPG
Elijah SarrattWR47 REC / 626 YDS / 11 TD / 62.6 YPG
Rolijah HardyLB64 TKL / 10 TFL / 7 SACK
Isaiah JonesLB48 TKL / 9 TFL / 5 SACK / 1 INT
Aiden FisherLB57 TKL / 5 TFL / 2.5 SACK / 2 INT
Louis MooreDB55 TKL / 2 TFL / 4 INT / 4 PD

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