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Reading: 2025-26 Men’s First Round Odds: Spreads, Lines for all 32 Games
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2025-26 Men’s First Round Odds: Spreads, Lines for all 32 Games
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2025-26 Men’s First Round Odds: Spreads, Lines for all 32 Games

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Last updated: March 20, 2026 6:38 am
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Published: March 20, 2026
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Let’s get down to business. 

Check out the odds for every first-round game in the men’s NCAA Tournament at DraftKings Sportsbook as of March 20.

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

THURSDAY, MARCH 19

No. 16 Siena 65, No. 1 Duke 71

Spread: Duke -28.5 (Siena covers)
O/U: 136.5 (Under hits)

No. 16 Howard 80, No. 1 Michigan 101

Spread: Michigan -30.5 (Howard covers)
O/U: 151.5 (Over hits)

No. 15 Idaho 47, No. 2 Houston 78

Spread: Houston -23.5 (Houston covers)
O/U: 137.5 (Under hits)

No. 14 Kennesaw State 64, No. 3 Gonzaga 73

Spread: Gonzaga -21.5 (Kennesaw State covers)
O/U: 152.5 (Under hits)

No. 14 North Dakota State 67, No. 3 Michigan State 92

Spread: Michigan State -15.5 (MSU covers)
O/U: 143.5 (Over hits)

No. 14 Penn 70, No. 3 Illinois 105

Spread: Illinois -25.5 (Illinois covers)
O/U: 151.5 (Over hits)

No. 13 Troy 47, No. 4 Nebraska 76

Spread: Nebraska -13.5 (Nebraska covers)
O/U: 139.5 (Under hits)

No. 13 Hawaii 78, No. 4 Arkansas 97

Spread: Arkansas -15.5 (Arkansas covers)
O/U: 158.5 (Over hits)

No. 12 High Point 83, No. 5 Wisconsin 82

Spread: Wisconsin -10.5 (HPU covers)
O/U: 162.5 (Over hits)

No. 12 McNeese 68, No. 5 Vanderbilt 78

Spread: Vanderbilt -12.5 (McNeese covers)
O/U: 149.5 (Under hits)

No. 11 South Florida 79, No. 6 Louisville 83

Spread: Louisville -4.5 (USF covers)
O/U: 161.5 (Over hits)

No. 11 VCU 82, No. 6 UNC 78 (OT)

Spread: UNC -2.5 (VCU covers)
O/U: 150.5 (Over hits)

No. 11 Texas 79, No. 6 BYU 71

Spread: BYU -2.5 (Texas covers)
O/U: 158.5 (Under hits)

No. 10 Texas A&M 63, No. 7 Saint Mary’s 50

Spread: Saint Mary’s -2.5 (A&M covers)
O/U: 148.5 (Under hits)

No. 9 TCU 66, No. 8 Ohio State 64

Spread: Ohio State -2.5 (TCU covers)
O/U: 146.5 (Under hits)

No. 9 Saint Louis 102, No. 8 Georgia 77

Spread: Georgia -2.5 (SLU covers)
O/U: 168.5 (Over hits)

FRIDAY, MARCH 20

No. 16 LIU vs. No. 1 Arizona

Spread: Arizona -30.5
Moneyline: Arizona -100000, LIU +5000
O/U: 149.5

No. 16 Prairie View vs. No. 1 Florida

Spread: Florida -35.5
Moneyline: Florida -100000, Prairie View +5000
O/U: 155.5

No. 15 Tennessee State vs. No. 2 Iowa State

Spread: ISU -24.5
Moneyline: ISU -8000, Tennessee State +2200
O/U: 148.5

No. 15 Queens U vs. No. 2 Purdue

Spread: Purdue -25.5
Moneyline: Purdue -8000, Queens U +2200
O/U: 162.5

No. 15 Furman vs. No. 2 UConn

Spread: UConn -20.5
Moneyline: UConn -4500, Furman +1700
O/U: 136.5

No. 14 Wright State vs. No. 3 Virginia

Spread: Virginia -18.5
Moneyline: Virginia -2800, Wright State +1300
O/U: 145.5

No. 13 Hofstra vs. No. 4 Alabama

Spread: Alabama -11.5
Moneyline: Alabama -800, Hofstra +550
O/U: 158.5

No. 13 Cal Baptist vs. No. 4 Kansas

Spread: Kansas -13.5
Moneyline: Kansas -1350, Cal Baptist +800
O/U: 138.5

No. 12 Akron vs. No. 5 Texas Tech

Spread: Texas Tech -7.5
Moneyline: Texas Tech -325, Akron +260
O/U: 155.5

No. 12 Northern Iowa vs. No. 5 St. John’s

Spread: St. John’s -9.5
Moneyline: St. John’s -535, UNI +400
O/U: 131.5

No. 11 Miami OH vs. No. 6 Tennessee

Spread: Tennessee -11.5
Moneyline: Tennessee -550, Miami OH +410
O/U: 149.5

No. 10 Missouri vs. No. 7 Miami FL

Spread: Miami -1.5
Moneyline: Miami -130, Missouri +110
O/U: 146.5

No. 10 Santa Clara vs. No. 7 Kentucky

Spread: Kentucky -3.5
Moneyline: Kentucky -155, Santa Clara +130
O/U: 157.5

No. 10 UCF vs. No. 7 UCLA

Spread: UCLA -5.5
Moneyline: UCLA -245, UCF +200
O/U: 152.5

No. 9 Utah State vs. No. 8 Villanova

Spread: Utah State -1.5
Moneyline: Utah State -125, Villanova +105
O/U: 146.5

No. 9 Iowa vs. No. 8 Clemson

Spread: Iowa -2.5
Moneyline: Iowa -130, Clemson +110
O/U: 128.5

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